A medical manipulator (1) includes an end effector (13), an elongated portion (14) connected to a proximal end side of the end effector, a first base end portion (20) connected to a proximal end side of the elongated portion (14), a first transmission unit (22) provided at the first base end portion (20) and configured to transmit power for operating the elongated portion (14) or the end effector (13) from the first base end portion (20), a second base end portion separably installed on the first base end portion (20), a drive unit (32) provided at the second base end portion and configured to generate the power for operating the end effector (13) and the elongated portion (14), a second transmission unit (38) provided at the second base end portion and configured to transmit the power generated by the drive unit (32) to the first transmission unit (22), a protruding portion (26) provided at the first transmission unit (22), engaged with the second transmission unit (38) in an installation process in which the first base end portion (20) is installed on the second base end portion and also configured to be rotatable to operate the elongated portion (14) or the end effector (13), an engaged portion (42) provided at the second transmission unit (38) to be engageable with the protruding portion (26) in the installation process of the first base end portion (20) on the second base end portion and configured to be rotatable by being pressed by the protruding portion (26) to be in a predetermined positional relationship based on a shape of the protruding portion (26) in an engagement process with the protruding portion (26), a control unit configured to provide an instruction to the drive unit (32), and an operation unit configured to provide an instruction to the control unit.