Stabilizing excipient for inactivated whole virus vaccine

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专利权人:

Sandrine Cigarini;Alain Francon;Michel Chevalier;Eric Calvosa;Nadege Moreno;Virginie Fabre

发明人:

Alain Francon,Michel Chevalier,Nadege Moreno,Eric Calvosa,Sandrine Cigarini,Virginie Fabre

申请号：

US12899492

公开号：

US08557253B2

申请日:

2010.10.06

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The invention relates to a vaccine composition comprising:a) inactivated whole virus, andb) a stabilizing excipient which comprises: i. a buffer solution,ii. a mixture of essential and nonessential amino acids,iii. a disaccharide,iv. a polyol,v. a chelating agent,vi. urea or a urea derivative, andvii. a nonionic surfactant.

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