ALIAGAS-MARTIN, IGNACIO,CRAWFORD, JAMES JOHN,MATHIEU, SIMON,RUDOLPH, JOACHIM,LEE, WENDY
申请号:
CA2854248
公开号:
CA2854248A1
申请日:
2012.12.21
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Compounds having the formula I wherein A, R1a, R1b, R2, R3, R4, R5, R6, R7, R8, Ra, Rb, X1, X2, X3 and n are as defined herein are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.