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Reduction of grid loss in patch production
专利权人:
Acino AG
发明人:
GRADER, Ludwig,PIOTROWSKI, Holger
申请号:
ES13700903
公开号:
ES2577886T3
申请日:
2013.01.21
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
Method for the production of systems for the transdermal or permucosal administration of active ingredients, the process comprising the following steps: - facilitation of a coated sheet of support sheet (10) comprising a strip of sheet of 5 support (1) with a coating (2) containing active ingredient adherent thereto, with active substance deposit surfaces (12) defined on the support foil web (10) coated in such a way that the active principle deposit surfaces (12) are arranged in the band direction (1) of the support foil band (10) covered in two or more rows such that the rows cannot be separated from each other in the band direction (1) by a straight line without cut, in this regard, active substance deposit surfaces (12), and because the percentage of the surface of the coated backsheet web (10) that is not used as a surface of deposit of active ingredient (12) without taking into account the edge areas of the coated support sheet band (10) amounts to less than 39% of the total surface of the coated support sheet band (10); and - separation (S4) of the support foil band (10) coated in the band direction (1) into two or more partial bands (15a, 15b, 15c, 15d) such that each partial band contains a row of active substance deposit surfaces (12), none of the active substance deposit surfaces (12) being cut during separation.Procedimiento para la producción de sistemas para la administración transdérmica o permucosa de principios activos, comprendiendo el procedimiento las siguientes etapas: - facilitación de una banda de lámina de soporte (10) recubierta que comprende una banda de lámina de 5 soporte (1) con un recubrimiento (2) que contiene principio activo adherente a la misma, estando definidas superficies de depósito de principio activo (12) sobre la banda de lámina de soporte (10) recubierta de tal manera que las superficies de depósito de principio activo (12) están dispuestas en la dirección de banda (1) de la banda de lámina de soporte (10) recubierta en dos
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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