BUSCHMANN, HELMUT, HEINRICH,VELA-HERNANDEZ, JOSE, MIGUEL,ZAMANILLO-CASTANEDO, DANIEL
申请号：
NZ58882909
公开号：
NZ588829A
申请日:
2009.04.24
申请国别(地区):
NZ
年份:
2013
代理人:
摘要：
ABSTRACT - 588829 The disclosure relates to a synergistic pharmaceutical combination of at least one sigma receptor ligand represented by formula (I) and at least one opioid or opiate compound that binds to opioid receptors selected from morphine or a structurally derivative thereof, fentanyl and tramadol, wherein the variables shown is formula (I) are as defined in the specification. This synergistic combination is suitable for the treatment of pain by potentiating the analgesic effect of morphine or a structurally derivative thereof, fentanyl or tramadol and/or for decreasing the dependency induced thereby.
