Trau, Matt,Shiddiky, Muhammad Johirul Alam,Rauf, Sakandar,Pudhukode Vaidyanathan, Ramanathan
申请号:
AU20180250349
公开号:
AU2018250349(A1)
申请日:
2018.10.15
申请国别(地区):
澳大利亚
年份:
2018
代理人:
摘要:
A method for the detection of target entities, the method including: introducing a liquid sample containing at least one type of target entity to be detected into a fluidic channel; wherein mutually spaced electrodes are disposed along the fluidic channel and are functionalised to selectively bond to the at least one type of target entity, the mutually spaced electrodes being configured to electro-hydrodynamically pump the liquid sample along the fluidic channel on application of a signal to the electrodes; selecting one or more parameters of a signal to be applied to the electrodes to provide enhanced selectivity of the at least one type of target entity by selectively shearing non-specifically adsorbed cells and/or molecules from the electrodes; and applying a signal having the selected one or more parameters to the electrodes to electro-hydrodynamically pump the liquid sample along the fluidic channel and capture the at least one type of target entity at the functionalised electrodes, wherein: (i) the sign