강릉원주대학교산학협력단;GANGNEUNG-WONJU NATIONAL UNIVERSITY INDUSTRY ACADEMY COOPERATION GROUP
发明人:
KIM, SANG MOO,김상무,CHOI, SEUNG HWA,최승화
申请号：
KR1020110035587
公开号：
KR1020120118170A
申请日:
2011.04.18
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A composition for preventing or treating colon cancers which includes stichopus extracts is provided to prevent side effects by including stichopus extracts as active ingredients. CONSTITUTION: A composition for preventing or treating colon cancers which includes stichopus extracts or fractions thereof. The Stichopus is a body wall or internal organs of the Stichopus. The Stichopus fractions are chloroform fraction, hexane fraction, ethylacetate fraction or butanol fraction. The concentration of the Stichopus extracts or the fractions is 0.1-0.4 mg/mL. The Stichopus extracts or the fractions are obtained by the following steps: extracting by adding 80% methanol to stichopus and vacuumed drying thereof； dissolving the dried extract in water and partitioning thereof with chloroform； and vacuum drying the fractions. [Reference numerals] (AA) Stichopus body wall and internal organs； (BB) Freeze drying； (CC) Grinding and filteration； (DD) 80% methanol extraction； (EE) Vacuum drying； (FF) Dissolving and solvent graduation； (GG) Vacuum drying； (HH) Stichopus fraction본 발명은 해삼 추출물 또는 이의 분획물을 포함하는 대장암 예방 또는 치료용 약학 조성물 및 식품 조성물에 관한 것이다.본 발명의 해삼 추출물을 포함하는 약학 조성물은 β-glucuronidase 저해활성을 갖고 있으므로 대장암 치료 또는 예방 효과가 있을 뿐만 아니라, 기존의 합성 대장암 치료물질과는 달리 천연물질인 해삼 추출물을 유효성분으로 포함하고 있으므로, 부작용 등이 문제되지 않는다.
