The Government of the United States of America; as represented by the Secretary; Department of Health and Human Services
发明人:
申请号:
EP10010354.8
公开号:
EP2333065B1
申请日:
2001.01.26
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention discloses the identification and isolation of novel MHC class II epitopes derived from the cancer antigen, NY ESO-1. The novel MHC class II epitopes from NY-EsO-1 are recognized by CD4 + T lymphocytes in an HLA class II restricted manner, in particular HLA-DR or HLA-DP restricted. The products of the gene are promising candidates for immunotherapeutic strategies for the prevention, treatment and diagnosis of patients with cancer.