DR. CHAVA SATYANARAYANA,DR.CHAVAKULA RAMADAS,DR. GORANTLA SEETA RAMANJANEYULU,KONUDULA BABU RAO
申请号：
IN623/CHE/2005
公开号：
IN265736B
申请日:
2005.05.24
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
A process for preparing Duloxetine, or its acid addition salt, which process comprises (i) condensation of (S)-(-)-N, N-dimethyl-3-(2-thienyl)-3 -hydroxy propanamine with 1-fluoronaphthalene followed by demethylation or condensation of N, N-dimethyl-3-(2-thienyl)-3-hydroxy propanamine with 1-fluoronaphthalene followed by resolution and demethylation and (ii) if desired, converting Duloxetine to its acid addition salt.
