An embodiment herein provides a local delivery device for targeted therapeutic effect. Accordingly, the local delivery device comprises a cap preferably a hemispherical cap, a locking part and a shaft part, wherein the local delivery device can be of a centre tightened local delivery device or a periphery tightened delivery device, wherein the hemispherical cap comprises a screw driver slot at its centre or at its periphery. The locking part has its outer surface threaded and includes a canister to accommodate the desired agent for delivery or can be made of substance intended with or without additives and bases. The locking part may be attached to the hemispherical cap. The shaft part includes unthreaded or threaded configuration and attached to the locking part. A locking hole provides an aperture to introduce the local delivery device to the plate or other implants of choice and bone underneath.
