CHARRIER JEAN DAMIEN,BINCH HAYLEY MARIE,HURLEY DENNIS JAMES,CLEVELAND THOMAS,JOSHI PRAMOD,FANNING LEV TYLER DEWEY,PINDER JOANNE,O DONNELL MICHAEL,VIRANI ANISA NIZARALI,KNEGTEL RONALD MARCELLUS ALPHONS
申请号：
IN3475/KOLNP/2012
公开号：
IN2012KN03475A
申请日:
2012.11.09
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention methods of treating various diseases, disorders, and conditions using the compounds of this invention processes for preparing the compounds of this invention intermediates for the preparation of the compounds of this invention and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena the study of intracellular signal transduction pathways mediated by such kinases and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I wherein the variables are as defined herein.
