Anders Sägström,Anna Dahlgren,Hakan Engqvist,Susanne Bredenberg
申请号：
BRPI1009121
公开号：
BRPI1009121A2
申请日:
2010.03.02
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
There is provided a sustained-release pharmaceutical composition comprising a solid, continuous network comprising an excipient with a high mechanical strength, which network also comprises pores, within which pores is interspersed a mixture of an active ingredient and a film-forming agent, characterized in that said pores are formed during the production of the composition. Compositions of the invention find particularly utility as abuse-resistant formulations comprising opioid analgesics that may be employed in the treatment of chronic pain.
