The present invention relates to a biopsy instrument, comprising the following components: i. a guide element (1) comprising a spring-elastic distal (2) region and a proximal (3) region ii. a biofunctionalized element (4) arranged between the distal and the proximal region of the guide element and whose surface has detection molecules, and iii. a stabilizing element (5) connected to the proximal region of the guide element. The invention further relates to the use of said biopsy instrument for enriching specific sample material from the body as well as to a biopsy kit and the use of the same for enriching specific sample material.
