The invention provides an antimicrobial adhesive comprising a plurality of particulates, a plurality of metallic particles and cyanoacrylate monomer. Each of the particulates attached numbers of the metallic particles on the surface to form a mixture having a specific gravity approximating to that of the cyanoacrylate monomer. Those particulates carrying metallic particles on the surface can be suspended well in the cyanoacrylate monomer without aggregation or precipitation while the cyanoacrylate monomer produces no pre-mature polymerization.