The present invention relates to a novel topical composition for treatment of the skin. The composition is a microemulsion that comprises curcumin or a curcumin derivative. The composition is able to penetrate into skin cells where it induces the production of adenosine triphosphate (ATP) and promotes the formation of new skin cells. The formation of new skin cells smoothes the skin and alleviates lines and wrinkles. The topical composition can be applied to the skin of a person daily. The invention also relates to the use of the novel topical composition for delaying skin aging. In another aspect, the invention relates to the use of the novel composition for reducing or preventing hair loss and/or inducing the growth of new hair.