MONOCLONAL ANTIBODIES AGAINST THE PBP2-A PROTEIN AND HOMOLOGOUS SEQUENCES FOR THE TREATMENT OF INFECTIONS BY AND IMMUNODIAGNOSTICS OF BACTERIA OF THE FIRMICUTES PHYLUM
Joao Luiz Sampaio Queiroz;Maria da Gloria Martins Teixeira;Nadia Maria Batoreu;Jose Procopio Moreno Senna
发明人:
Jose Procopio Moreno Senna,Joao Luiz Sampaio Queiroz,Nadia Maria Batoreu,Maria da Gloria Martins Teixeira
申请号：
US13389860
公开号：
US20120195907A1
申请日:
2010.08.10
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to monoclonal antibodies capable of recognising and binding to the PBP2-a protein and to other proteins having sequences homologous to PBP2-a, including pathogenic species such as the methyciline-resistant Staphylococcus Aureus (MRSA), coagulase-negative Staphilococcus, Staphylococcus sciuri and Enterococcus, and any other bacteria containing the PBP2-a protein or homologous sequences. The invention also relates to the use of the monoclonal antibodies capable of recognising and binding to the PBP2-a protein and to other proteins having sequences homologous to PBP2-a in a complementary immunodiagnostic test for detecting resistance to beta-lactam antibiotics.
