ANALOGUES DE CARBA-NUCLEOSIDE POUR UN TRAITEMENT ANTIVIRAL

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专利权人:

GILEAD SCIENCES; INC.

发明人:

CHO, AESOP,KIM, CHOUNG U.,PARRISH, JAY,XU, JIE

申请号：

CA2722084

公开号：

CA2722084C

申请日:

2009.04.22

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Provided are imidazol [1,5-f] [1,2.4]triazinyl, imidazol [1,2,4]triazinyl, and[1,2,4]triazolo [4,3-f] [1,2,4] triazinyl nucleosides of formula I, nucleosidephosphates andprodrugs thereof, wherein X1 or X2 is independently C-R10 or N and wherein atleast oneof X1 and X2 is N. The compounds, compositions, and methods provided may beusefulfor the treatment of Flaviviridae virus infections, particularly hepatitis Cinfections.(see formula I)

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http://www.ckcest.cn/home/