Provided are methods for enhancing exercise (e.g., intense, eccentric, elevated temperature, repetitive, aerobic, and high altitude) performance, comprising administering electrokinetically-altered aqueous fluids comprising an ionic aqueous solution of stably configured charge-stabilized oxygen-containing nanostructures predominantly having an average diameter of less than 100 nanometers. In certain aspects, enhancing exercise performance comprises at least one of: reducing plasma inflammatory cytokines (e.g., IFN-alpha, ENA-78 and BDNF) ameliorating muscle/tendon damage or enhancing muscle/tendon recovery reducing biomarkers of exercise-induced muscle injury (e.g., CK, plasma myoglobin) ameliorating exercise induced tendinosis, tendonitis, tenosynovitis, avulsion, and tendon strain associated with chronic repetitive movement or enhancing recovering therefrom increasing VO2 max decreasing RPE reducing blood lactate preserving muscle contractile function (e.g., maximal force, joint ROM) reducing muscle soreness ameliorating onset of fatigue in an excercising subject. Improved methods for producing electrokinetically altered aqueous fluids (including sports beverages) are also provided.Linvention porte sur des procédés damélioration des performances dexercice (par exemple intense, excentrique, à température élevée, répétitif, aérobic, et à haute altitude) comprenant ladministration de fluides aqueux modifiés électrocinétiquement, comprenant une solution aqueuse ionique de nanostructures contenant de loxygène stabilisées en charges, configurées de manière stable ayant de manière prédominante un diamètre moyen inférieur à 100 nanomètres. Selon certains aspects, lamélioration des performances dexercice comprend au moins lune parmi les opérations suivantes : réduction des cytokines inflammatoires dans le plasma (par exemple IFN-alpha, ENA-78 et BDNF) amélioration des lésions musculaires/ des tendons ou amélioration de la récupération musculaire/des tendons réduction des b