Nigel William Fraser;Susanne Moira Brown;Alasdair Roderick MacLean;Bruce Paul Randazzo
发明人:
Alasdair Roderick MacLean,Susanne Moira Brown,Nigel William Fraser,Bruce Paul Randazzo
申请号:
US13305516
公开号:
US20120141418A1
申请日:
2011.11.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Use as an anti-cancer agent of a mutant herpes simplex virus wherein the mutant virus comprises a modification in the γ34.5 gene in the long repeat region (RL) such that the γ34.5 gene is a non-functional, manufacture of medicaments and methods of testing cancer in mammals employing HSV mutant.