This disclosed subject matter concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.本揭露標的係有關於核酸分子,及其經由對於鞘翅目害蟲中的標的編碼序列與所轉錄的非編碼序列之RNA干擾媒介型抑制作用而用於防治鞘翅目害蟲之方法。本揭露內容亦有關於用於產生表現適用於防治鞘翅目害蟲的核酸分子之基因轉殖型植物之方法,及由此獲得的植物細胞與植物。