FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA);INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANCATS
发明人:
GOMIS, ROGER,PLANET, EVARIST,PAVLOVIC, MILICA,ARNAL, ANNA,TARRAGONA, MARIA
申请号：
CA2906394
公开号：
CA2906394A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to a method for the prognosis of bone metastasis in cancer which comprises using a probe to determine if a gene of interest is amplified in a primary tumor sample. Likewise, the invention also relates to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise using a probe to determine the expression level of a gene of interest, or the amplification or translocation of a gene of interest. The invention also relates to a method for predicting early bone metastasis in a subject suffering cancer. The invention also relates to a c-MAF inhibitor as therapeutic agent for use in the treatment of cancer metastasis. The invention relates to kits for predicting bone metastasis and predicting the clinical outcome of a subject suffering from bone metastasis. Finally, the invention relates to a method for typing of a subject suffering cancer and for classifying a subject from cancer into a cohort.
