METHODS AND COMPOSITIONS FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR-1alpha (PGC1alpha) AS A TARGET OF CIRCULATING TUMOR CELLS

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专利权人:

发明人:

Raghu Kalluri,Valerie S. Lebleu

申请号：

US14400687

公开号：

US20150166642A1

申请日:

2013.05.15

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to methods, compositions, and diagnostic tests for treating and diagnosing a metastatic as disease that results in increased mitochondrial respiration and/or biogenesis. In particular, the methods and compositions include treatment of metastatic diseases such as breast cancer using an antagonist of mitochondrial respiration such as a PGC1α antagonist.

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中国工程科技知识中心

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http://www.ckcest.cn/home/