Marc D. Chioda;Yan Guo;Harry R. Chobanian;Wenping Li;Ravi P. Nargund;Terence G. Hamill;Darrell Arthur Henze;Linus S. Lin;Ping Liu;Robert J. DeVita
发明人:
Harry R. Chobanian,Linus S. Lin,Ping Liu,Marc D. Chioda,Robert J. DeVita,Ravi P. Nargund,Yan Guo,Terence G. Hamill,Wenping Li,Darrell Arthur Henze
申请号:
US13574303
公开号:
US20130030000A1
申请日:
2011.01.25
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed to a composition useful for the treatment of a FAAH mediated disease, disorder or conditions comprising a FAAH inhibitor and a second activation, comprising a selected imidazole or oxazole FAAH inhibitor and a second active agent. The compositions will be useful in the treatment of a wide range of disease, disorder, or conditions including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzheimer disease, and Parkinson's disease. In another aspect the invention discloses herein is directed to compositions useful in the treatment of neuropathic and nociceptive pain, said compositions comprising etoricoxib.