AKTOUDIANAKIS, EVANGELOS,CHIN, GREGORY,CORKEY, BRITTON KENNETH,DU, JINFA,ELBEL, KRISTYNA,JIANG, ROBERT H.,KOBAYASHI, TETSUYA,MARTINEZ, RUBEN,METOBO, SAMUEL E.,MISH, MICHAEL,SHEVICK, SOPHIE,SPERANDIO,
申请号:
SG11201507926R
公开号:
SG11201507926RA
申请日:
2014.03.27
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I) wherein R1a, R1b, R2a, R2b, R3, and X are described herein.