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Polyethylene glycol derivative
专利权人:
日本新薬株式会社
发明人:
園家 暁,上田 稔浩
申请号:
JP2008557092
公开号:
JP5347510B2
申请日:
2008.02.04
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
Disclosed are: a novel polyethylene glycol derivative; a drug carrier comprising the derivative; and a pharmaceutical composition comprising the drug carrier having a pharmacologically active substance included therein. Specifically disclosed are: a polyethylene glycol derivative represented by the general formula (I); a drug carrier comprising the derivative and 2-0-(2-diethylaminoethyl)carbamoyl- 1,3-O-dioleoyl-glycerol; and a pharmaceutical composition comprising the drug carrier and a pharmacologically active substance (preferably double-stranded RNA, double-stranded DNA or an oligonucleic acid). Wherein R represents a saturated or unsaturated aliphatic hydrocarbon group having 10 to 30 carbon atoms or a saturated or unsaturated fatty acid residue having 10 to 30 carbon atoms; and n represents an integer of 30 to 150.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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