Grillberger, Leopold,Reiter, Manfred,Fleischanderl, Daniel,Bramberger, Gregor
申请号:
AU2011274470
公开号:
AU2011274470A1
申请日:
2011.07.08
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Among other aspects, the present invention relates to cell culture conditions for producing high molecular weight vWF, in particular, highly multimericWF with a high specific activity and ADAMTS13 with a high specific activity. The cell culture conditions of the present invention can include, for example, a cell culture medium with an increased copper concentration and/or cell culture supernatant with a low ammonium (NH