ELIGLIUSTATAS (GENZ 112638) KAIP GLIUKOZILCERAMIDO SINTAZĖS SLOPIKLIS, SKIRTAS NAUDOTI FABRI ARBA GOŠĖ LIGOS GYDYMO BŪDE, KUR BŪDAS APIMA INDIVIDUALIOS TERAPINĖS DOZĖS PRIDERINIMĄ PACIENTO P-450 METABOLIZMUI
The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.
