An oral care composition is provided which comprises a therapeutically effective amount of at least one ionic liquid for use in removing or reducing plaque, inhibiting the amount of bacteria in an oral cavity, inhibiting biofilm formation and/or degradation in an oral cavity and teeth whitening.本發明提供一種口腔保健組成物,其包含醫療有效量之至少一種離子性液體,用於移除或減少菌斑、抑制口腔中細菌數量、抑制口腔中生物膜形成及/或降解生物膜、及美白牙齒。