活化ＡＭＰＫ（腺苷單磷酸活化的蛋白質激酶）之吲哚和吲唑類化合物农业专利-农业学术服务平台

发明人:: BHATTACHARYA, SAMIT KUMAR,巴特卡亚　沙米特,巴特卡亞　沙米特,CAMERON, KIMBERLY O'KEEFE,坎隆　金伯利,DOWLING, MATTHEW SCOTT,道林　马修,道林　馬修,EBNER, DAVID CHRISTOPHER,艾柏纳　大卫,艾柏納　大衛,FERNANDO, DILINIE PRASADHINI,法兰度　迪林尼,法蘭度　迪,巴特卡亚沙米特,巴特卡亞沙米特,CAMERON, KIMBERLY OKEEFE,坎隆金伯利,道林马修,道林馬修,艾柏纳大卫,艾柏納大衛,法兰度迪林尼,法蘭度迪林

摘要：: The present invention relates to indole and indazole compounds of Formula (I) that activate 5' adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, or disorders ameliorated by activation of AMPK.本發明係有關活化5’-腺苷單磷酸活化的蛋白質激酶(AMPK)之式(I)所示的吲哚和吲唑類化合物：本發明亦包括含有這些化合物的藥學組成物及治療或預防可經由活化AMPK而改善的疾病、病況、或失調症之方法。