A syringe interface between a piston and plunger is provided. The syringe interface includes a piston configured to be driven by an injector and a syringe. The syringe includes: a syringe barrel having a proximal end and a distal end； and a plunger having a proximal end, a distal end, and a sidewall extending therebetween. The plunger is slidably inserted in the syringe barrel such that the sidewall of the plunger forms a moveable seal against an inner surface of the syringe barrel. The piston is configured to form a removable suction engagement with the plunger for advancing or retracting the plunger through the syringe barrel as the piston is driven by the injector. A method for filling a syringe including a suction interface between a piston and plunger, as well as a filling station including a vacuum source, such as a vacuum pump, are also provided.
