Paul David Johnson;Jeffrey James Morris;Andrew Leach;Zbigniew Stanley Matusiak;Richard William Arthur Luke
发明人:
Paul David Johnson,Andrew Leach,Richard William Arthur Luke,Zbigniew Stanley Matusiak,Jeffrey James Morris
申请号：
US13324191
公开号：
US20120190679A1
申请日:
2011.12.13
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to a novel group of compounds of Formula (I) or salts thereof:wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).
