An obstructive sleep apnea (OSA) suppression system includes a respiration monitoring device for detecting one or more OSA incidents, the respiration monitoring device including one or more of an accelerometer, a CO2 sensor, an oximeter or an audio sensing device. The OSA system further includes a patch adapted to be externally coupled on a dermis of a user, the patch including a flexible substrate and an adhesive on a first side adapted to adhere to the dermis of the user, an electronic package directly coupled to the substrate, the electronic package including a processor, and electrodes directly coupled to the substrate and the electronic package.