DNA sequence of TAT, gene construct, vaccine and methods thereof

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专利权人:

ジャワハーラル ネール センター フォー アドヴァンスド サイエンティフィック リサーチ

发明人:

ランガ、ウダイクマール

申请号：

JP2011509084

公开号：

JP5576859B2

申请日:

2009.05.14

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The present invention relates to non toxic, immunogenic viral Tat DNA sequences comprising wherein the Tat Sequence is rendered non toxic and immunogenic by insertion of T-Helper Epitope into the Cysteine-rich domain, or Basic domain or Core domain of said Tat DNA sequence, optionally along with insertion of a synthetic Intron between C-terminal region and Exon II region of the Tat DNA Sequence. The present invention also relates to elongation factor promoter constructs and process thereof. Also the present invention relates to a process of obtaining the non toxic and immunogenic Tat DNA sequence and vaccine and a method thereof.

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中国工程科技知识中心

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http://www.ckcest.cn/home/