Optimized Fc variants
- 专利权人:
- Xencor; Inc.
- 发明人:
- Gregory Lazar,Wei Dang,John Desjarlais,Sher Karki,Omid Vafa,Robert Hayes,Jost Vielmetter
- 申请号：
- US14326373
- 公开号：
- US09663582B2
- 申请日:
- 2014.07.08
- 申请国别(地区):
- US
- 年份:
- 2017
- 代理人:
- 摘要：
- The present invention relates to Fc variants having decreased affinity for FcγRIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.
- 来源网站：
- 中国工程科技知识中心
