GROMADA, JESPER,GUSAROVA, VIKTORIA,MURPHY, ANDREW J.
申请号:
CA3014928
公开号:
CA3014928A1
申请日:
2017.02.13
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention provides methods and compositions for treating or preventing atherosclerosis in a subject. The methods of the present invention comprise administering an inhibitor of angiopoietin-like protein-3 (ANGPTL3) to a subject who has atherosclerosis or is at risk of developing atherosclerosis. In certain embodiments, the ANGPTL3 inhibitor is an antibody or antigen-binding fragment thereof that specifically binds ANGPTL3.