DEATH ASSOCIATED PROTEIN 1 VARIANTS AND USE THEREOF FOR MODULATING AUTOPHAGY

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专利权人:

Adi Kimchi

发明人:

Adi Kimchi,Itay Koren

申请号：

US13583924

公开号：

US20130005651A1

申请日:

2011.03.10

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention relates to methods for the modulation of autophagy by altering the phosphorylation of Death Associated Protein (DAP1). The present invention further relates to methods of treating autophagy associated diseases comprising the suppression of autophagy by dephosphorylating DAP1. The invention further provides human DAP1 mutated at positions 3 and 51 with phospho-silencing residues and uses thereof in treating autophagy associated diseases.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/