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Quantification of the relative amount of water in the tissue microcapillary network
专利权人:
CR Development AB
发明人:
Daniel Topgaard,Samo Lasic
申请号:
US14410549
公开号:
US10031204B2
申请日:
2013.06.24
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention discloses a method for magnetic resonance (MR) imaging comprising: acquiring at least two MR images with different motion-weighting originating from a RF and gradient pulse sequence causing signal attenuation from diffusion but not flow (flow-compensated data); acquiring at least two MR images with different motion-weighting originating from a RF and gradient pulse sequence causing signal attenuation from diffusion and flow (non-compensated data); performing a model fit to the flow-compensated and non-compensated data in which at least one of the adjustable parameters are constrained to be the same for both sets of data; and obtaining quantitative information on microscopic flow by extracting at least one parameter of the intravoxel incoherent motion (IVIM) effect from the model fit, said method being directed to diffusion-perfusion.
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