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NOVE FARMACEUTSKE KOMPOZICIJE, OTPORNE NA ZLOUPOTREBU, ZA TRETMAN ZAVISNOSTI OD OPIOIDA
专利权人:
Orexo AB
发明人:
FISCHER, Andreas
申请号:
MEP201571
公开号:
ME02153B
申请日:
2012.09.18
申请国别(地区):
ME
年份:
2015
代理人:
摘要:
There is provided a tablet suitable for sublingual administration comprising microparticles of a pharmacologically-effective amount of buprenorphine, or a pharmaceutically-acceptable salt thereof; particles of a pharmacologically-effective amount of naloxone or a pharmaceutically-acceptable salt thereof; a disintegrant; and particles of a weak acid provided in a sufficient amount to enable the provision of a pH of between about 4.0 and about 6.5 and maintenance of pH within that range for no more than about 3 minutes after administration to a patient.text
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