Barton F. HAYNES,Hua-Xin LIAO,Bette T. KORBER,Peter T. HRABER
申请号:
US15539573
公开号:
US20180271973A1
申请日:
2015.12.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
In certain aspects the invention provides a selection of HIV-1 envelopes suitable for use as immunogens, and methods of using these immunogens in vaccination to induce neutralizing antibodies. In certain embodiments, the immunogens are designed to trimerize. In other embodiments, the immunogens and methods of using these comprise an immune modulating component.