A surgical stapling device is provided for sequentially applying a plurality of fasteners to body tissue and simultaneously incising tissue. The surgical stapling device includes an elongated body which is adapted to receive a single use loading unit ("SULU") or a disposable loading unit ("DLU") having staples in linear rows whose length can be between about 30mm and 60mm. Each DLU includes a proximal body portion, a mounting assembly and a tool assembly. The proximal body portion has a proximal end having one or more lugs which are dimensioned to be received within one or more channels formed in the distal end of the elongated body. The distal end of the walls defining the channels can be chamfered or angled such that if the DLU is not properly aligned with the elongated body when the proximal end of the DLU is inserted into the distal end of the elongated body, the chamfered or angled distal ends of the walls defining the channels will cam the lugs to properly align the DLU with the elongated body.