UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION;UNIVERSIDAD DE SANTIAGO DE CHILE;UPMC
发明人:
WAGNER, WILLIAM R.,VELANKAR, SACHIN SHANKAR,YE, SANG HO,TZENG, EDITH,POCIVAVSEK, LUKA,CERDA, ENRIQUE
申请号：
CA3079536
公开号：
CA3079536A1
申请日:
2017.10.18
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to substrates and composites having dynamic, reversible micron-level luminal surface deformation including texture or geometric instabilities, e.g., surface wrinkling and folding. The surface deformation and its reversal to the original surface form or to another, different surface form, is effective to reduce or prevent surface fouling and, more particularly, in certain applications, to reduce or prevent unwanted platelet adhesion and thrombus formation. The substrates and composites include a wide variety of designs and, more particularly, biomedical-related designs, such as, synthetic vascular graft or patch designs.
