It is intended to provide a method and compositions for stabilizing reduced coenzyme Q10 which is useful in foods, foods with nutrient function claims, foods for specified health uses, nutritional supplements, eutrophics, animal medicines, drinks, feeds, cosmetics, medicines, therapeutics, preventives and so on; a composition comprising reduced coenzyme Q10, a fat (excluding olive oil) and/or a polyol, in which the stabilization of the reduced coenzyme Q10 is not substantially inhibited; and a reduced coenzyme Q10-containing composition comprising reduced coenzyme Q10, a polyglycerol fatty acid ester and a fat and/or a polyol.本發明係提供一種可應用於食品、營養機能食品、特定保健用食品、營養輔助劑、營養劑、動物藥、飲料、飼料、化粧品、醫藥品、治療藥、預防藥等之還原型輔酶Q10之安定化方法及其組成物。係製成由含有還原型輔酶Q10(惟,除去橄欖油)及/或多元醇所構成,且對於還原型輔酶Q10之安定化實質上不會阻害之組成物。又,係製成含有還原型輔酶Q10、聚甘油脂肪酸酯及油脂及/或多元醇之含還原型輔酶Q10組成物。