A method and system 100 or maintaining iso center constant while dynamically changing the area of interest during an imaging procedure is disclosed herewith. The method comprises: allowing a user to move from an initial area of interest to new area of interest by allowing permissible axes motions, permissible axes including gantry axes, table axes and tilt movement of patient table 140 and dynamically calculating the iso center point while moving from an initial area of interest to a new area of interest as a function of relative distance between the areas of interest and as a function of parameters indicating relative motion of permissible axes. The method further comprises: identifying the area of interest by using at least one permissible axis motion and calculating the iso center point at the new area of interest after locking all the permissible axes motions except table tilt axis movement.
