invention Topoisomerase (topoisomerase) I and II inhibitors useful in the novel 2,4 -diphenyl -6- aryl pyridine-based compound , provides a method for their preparation and compositions containing them , since the compounds according to the invention are topoisomerase (topoisomerase) strongly inhibited the activity and cancer cell lines I and II , cancer is available as a medicament for the treatment and prevention of diseases .본 발명은 토포아이소머라제 (topoisomerase) I 및 II 활성 억제제로 유용한 신규한 2,4-디페닐-6-아릴 피리딘 계 화합물, 이의 제조방법 및 이를 포함하는 조성물을 제공하며, 본 발명에 따른 화합물은 토포아이소머라제 (topoisomerase) I 및 II 활성 및 암세포주를 강력하게 억제하므로, 암질환의 치료 및 예방을 위한 약제로 이용가능하다.
