Chan, Kyle W. H.,Hariri, Robert J.,Moutouh-De Parseval, Laure A.,Stirling, David I.
申请号:
AU2015201121
公开号:
AU2015201121A1
申请日:
2015.03.04
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
#$%^&*AU2015201121A120150326.pdf#####Abstract The present invention relates to methods of modulating mammalian stem cell and progenitor cell differentiation. The methods of the invention can be employed to regulate and control the 5 differentiation and maturation of mannalian, particularly human stem cells along specific cell and tissue lineages. The methods of the invention relate to the use of certain small organic molecules to modulate the differentiation of stem or progenitor cell populations along specific cell and tissue lineages, and in particular, to the differentiation of embryonic-lke stem cells originating from a postpartum placenta or for the differentiation of early progenitor cells to a 0 granulocytic lineage. Finally, the invention relates to the use of such differentiated stem or progenitor cells in transplantation and other medical treatments.