A new process for the manufacturing of the compound 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile 701

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专利权人:

ASTRAZENECA AB

发明人:

JANSSON, ANNETTE,HEDBERG, MARTIN,THIERING, SWANTJE,RADEVIK, ANDREAS,RYBERG, PER,DELISSER, VERN

申请号：

AU2008241602

公开号：

AU2008241602B2

申请日:

2008.04.17

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention relates to a new process for the manufacture of the compound 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]-indole-5-carbonitrile as a free base and pharmaceutically acceptable salts thereof, particularly the 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]-indole-5-carbonitrile citrate, and to new intermediates prepared in said process suitable for large scale manufacturing of said compound.

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