BRIAN E. FINK,ASHVINIKUMAR V. GAVAI,GREGORY D. VITE,PING CHEN,HAROLD MASTALERZ,DEREK NORRIS,JOHN S. TOKARSKI,YUFEN ZHAO,WEN-CHING HAN
申请号：
MYPI 20045093
公开号：
MY145634A
申请日:
2004.12.09
申请国别(地区):
MY
年份:
2012
代理人:
摘要：
THE PRESENT INVENTION PROVIDES COMPOUNDS OF FORMULA I AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF. THE FORMULA I COMPOUNDS INHIBIT TYROSINE KINASE ACTIVITY OF GROWTH FACTOR RECEPTORS SUCH AS HER1, HER2 AND HER4 THEREBY MAKING THEM USEFUL AS ANTIPROLIFERATIVE AGENTS. THE FORMULA I COMPOUNDS ARE ALSO USEFUL FOR THE TREATMENT OF OTHER DISEASES ASSOCIATED WITH SIGNAL TRANSDUCTION PATHWAYS OPERATING THROUGH GROWTH FACTOR RECEPTORS.
