Use of banana peel extract in the manufacture of a composition is provided, wherein the composition is for at least one of increasing expression ofTPH1gene, increasing expression ofDDCgene and increasing expression ofAANATgene. Accordingly, the composition is effective in treating, preventing or adjusting diseases or physiological functions related withTPH1,DDCand/orAANATgenes.一種使用香蕉皮萃取物於製造一組合物之用途,其中該組合物係用於以下之至少一者:提升TPH1基因表現、提升DDC基因表現、及提升AANAT基因表現,從而達到治療、預防或調節與TPH1基因、DDC基因及/或AANAT基因相關之疾病或生理機能的效果。
