Brenda L. Stevens,Alison Witte,Mark W. Rixon,Josephine M. Cardarelli,Thomas D. Kempe,Scott R. Presnell,Mohan Srinivasan,Susan C. Wong,Guodong Chen,Hui Wei,Stanley R. Krystek,Lumelle A. Schneeweis,Paul
申请号:
US13898544
公开号:
US08945553B2
申请日:
2013.05.21
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to antagonizing the activity of IL-17A, IL-17F and IL-23 using bispecific antibodies that comprise a binding entity that is cross-reactive for IL-17A and IL-17F and a binding entity that binds IL-23p19. The present invention relates to novel bispecific antibody formats and methods of using the same.