Methods for reducing the risk of a thromboembolic event, and a related drugdelivery system areprovided. In some embodiments, a dose of acetylsalicyhc acid can be providedin powder formto a patient using a dry powder inhaler. The dose can be effective to reduce arisk of athromboembolic event in a patient. A dry powder inhaler used for the methodcan have amouthpiece, a reservoir for receiving the dose of acetylsalicyhc acid, and anactuation memberfor making available the dose of acetylsalicyhc acid for inhalation by apatient through themouthpiece.